refractive errors

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	167
interventional	141
Observational	23
Registry	3

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Device	113
Procedure	8
Other	7
Drug	4
Device|Procedure	3
Device|Drug	2
Behavioral|Other	1
Combination Product	1
Dietary Supplement	1
Drug|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	50
NA	36
United Kingdom	11
Canada	9
Mexico	5
Australia	4
Germany	4
Japan	4
China	3
India	2
Brazil	1
China|India	1
China|United Kingdom	1
Croatia	1
Iran, Islamic Republic of	1
Nepal	1
New Zealand|Philippines|Singapore	1
Singapore	1
Sweden	1
Tanzania	1
United States|Canada	1
United States|Canada|Germany	1
United States|Canada|United Kingdom	1

Sites per Study

Site_count	Study_Count
1	102
2	10
3	5
4	4
5	5
6	3
7	2
8	2
9	1
10	2
11	1
15	1
17	1
20	1
23	1

Phase

Phase	Study_Count
N/A	125
Phase 4	7
Phase 3	5
Phase 2	2
Phase 2/Phase 3	2

Number of Arms

Number_of_Arms	Count_of_Studies
1	19
2	92
3	12
4	10
6	1
12	1
NA	6

Enrollment Metrics by Phase

Measure	N.A	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	3.000	33.00	92.0	36	10.0000
1st Qu.	49.000	49.75	130.5	38	47.5000
Median	83.500	66.50	169.0	61	55.0000
Mean	8413.048	66.50	169.0	152	408.4286
3rd Qu.	162.500	83.25	207.5	170	77.5000
Max.	1000000.000	100.00	246.0	455	2544.0000

Trial Group Type

group_type	Group_Count
Other	113
Experimental	96
Active Comparator	76
No Intervention	7
NA	6
Placebo Comparator	4
Sham Comparator	1

Intervention Model

intervention_model	Study_Count
Crossover Assignment	61
Parallel Assignment	51
Single Group Assignment	27
Factorial Assignment	1
NA	1

Primary Purpose

primary_purpose	Study_Count
Treatment	83
NA	18
Other	13
Supportive Care	12
Prevention	5
Device Feasibility	3
Basic Science	2
Diagnostic	2
Screening	2
Health Services Research	1

Observational Studies

Studies by Country

Country	Study_Count
China	6
United States	4
France	3
NA	2
Austria	1
Germany	1
Singapore	1
Spain	1
Turkey	1
United Kingdom	1
United States|Austria	1
United States|Haiti	1

Sites per Study

Site_count	Study_Count
1	20
2	3

Enrollment Metrics

Measure	Observational
Min	25.00
1st Qu	50.00
Median	150.00
Mean	42377.91
3rd Qu	1323.00
Max	852441.00

Observation Model

observational_model	Study_Count
Cohort	11
NA	5
Case-Control	3
Other	3
Case-Only	1

Time Perspective

time_perspective	Study_Count
Prospective	13
Cross-Sectional	4
Retrospective	4
NA	2

Registries

Studies by Country

Country	Study_Count
Poland	2
United States	1

Sites per Study

Site_count	Study_Count
1	3

Enrollment Metrics

Measure	Registries
Min	100.0000
1st Qu	100.0000
Median	100.0000
Mean	223.6667
3rd Qu	285.5000
Max	471.0000

Registry Model

observational_model	Study_Count
Cohort	2
Case-Crossover	1

Time Perspective

time_perspective	Study_Count
Prospective	3

Follow-up

target_duration	Study_Count
1 Day	1
24 Months	1
3 Months	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03341923	Clinical Evaluation of DAILIES TOTAL 1® Multifocal Compared to 1-Day Acuvue® Moist® Multifocal in a Japanese Population	https://ClinicalTrials.gov/show/NCT03341923	Completed	Alcon Research	2018-06-05
NCT03319212	Clinical Characterization of Symptomatic Populations	https://ClinicalTrials.gov/show/NCT03319212	Completed	Johnson & Johnson Vision Care, Inc.	2018-08-15
NCT03312257	Bifocal & Atropine in Myopia (BAM) Study	https://ClinicalTrials.gov/show/NCT03312257	Active, not recruiting	Ohio State University	2020-06-30
NCT03305770	DD T2 Daily Disposable Registration Trial	https://ClinicalTrials.gov/show/NCT03305770	Completed	Alcon Research	2018-02-21
NCT03278587	Village-Integrated Eye Worker Trial II - Pilot	https://ClinicalTrials.gov/show/NCT03278587	Recruiting	Francis I. Proctor Foundation	2020-08-31
NCT03169153	Clinical Comparison of Silicone Hydrogel Monthly Lenses	https://ClinicalTrials.gov/show/NCT03169153	Completed	Alcon Research	2018-07-19
NCT03118934	Assessing Fitting Guides in Alcon Multifocal Contact Lenses	https://ClinicalTrials.gov/show/NCT03118934	Completed	Alcon Research	2017-07-07
NCT03095027	Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear	https://ClinicalTrials.gov/show/NCT03095027	Completed	Alcon Research	2017-05-15
NCT03034928	Clinical Biocompatibility Evaluation of Contact Lens Coatings	https://ClinicalTrials.gov/show/NCT03034928	Completed	Alcon Research	2017-03-14
NCT03026257	Clinical Assessment of a HYDRAGLYDE® Regimen	https://ClinicalTrials.gov/show/NCT03026257	Completed	Alcon Research	2017-08-18
NCT02939170	Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks	https://ClinicalTrials.gov/show/NCT02939170	Completed	Alcon Research	2016-12-02
NCT02886923	Evaluation of Vision Effects of a Cosmetic Tinted Hydrogel Contact Lens	https://ClinicalTrials.gov/show/NCT02886923	Completed	Johnson & Johnson Vision Care, Inc.	2017-01-23
NCT02871375	Clinical Assessment of DAILIES TOTAL1® (DT1) Multifocal	https://ClinicalTrials.gov/show/NCT02871375	Completed	Alcon Research	2016-11-14
NCT02771145	Clinical Evaluation of the Safety and Efficacy of FID 120947A	https://ClinicalTrials.gov/show/NCT02771145	Completed	Alcon Research	2017-01-10
NCT02750813	ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®	https://ClinicalTrials.gov/show/NCT02750813	Completed	Alcon Research	2016-08-17
NCT02710292	Clinical Evaluation of DAILIES TOTAL 1® Performance in a Japanese Population	https://ClinicalTrials.gov/show/NCT02710292	Completed	Alcon Research	2016-09-14
NCT02699684	Comparison of Lotrafilcon B Lenses With Different Packaging Solutions	https://ClinicalTrials.gov/show/NCT02699684	Completed	Alcon Research	2016-10-20
NCT02696317	Clinical Evaluation of ACUVUE® OASYS® 1-Day and ACUVUE® OASYS®	https://ClinicalTrials.gov/show/NCT02696317	Completed	Alcon Research	2016-06-06
NCT02694835	Initial Performance of a Modified Daily Disposable Contact Lens	https://ClinicalTrials.gov/show/NCT02694835	Completed	Alcon Research	2016-04-11
NCT02675751	Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studioâ„¢ System and Star S4 IRâ„¢	https://ClinicalTrials.gov/show/NCT02675751	Completed	Abbott Medical Optics	2018-07-27
NCT02607384	The Baltimore Reading and Eye Disease Study	https://ClinicalTrials.gov/show/NCT02607384	Completed	Johns Hopkins University	2016-07-31
NCT02553681	Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D	https://ClinicalTrials.gov/show/NCT02553681	Completed	Contamac Ltd	2017-02-28
NCT02528123	VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia	https://ClinicalTrials.gov/show/NCT02528123	Active, not recruiting	London Vision Clinic	2020-09-30
NCT02517567	DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation	https://ClinicalTrials.gov/show/NCT02517567	Completed	Alcon Research	2016-04-22
NCT02515994	Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens	https://ClinicalTrials.gov/show/NCT02515994	Completed	Johnson & Johnson Vision Care, Inc.	2015-11-30
NCT02495948	Comparison of Two Marketed Silicone Hydrogel Lenses	https://ClinicalTrials.gov/show/NCT02495948	Completed	Alcon Research	2015-10-31
NCT02484586	Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses	https://ClinicalTrials.gov/show/NCT02484586	Completed	Brien Holden Vision	2017-02-07
NCT02402127	Lubricity Post-Wear - Competitive Lenses Pilot	https://ClinicalTrials.gov/show/NCT02402127	Completed	Alcon Research	2015-07-31
NCT02388763	Clinical Evaluation of MyDay™ and 1-DAY ACUVUE® TruEye®	https://ClinicalTrials.gov/show/NCT02388763	Completed	Alcon Research	2015-09-30
NCT02293538	Formula Identification (FID) 114657 in Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT02293538	Completed	Alcon Research	2015-07-31
NCT02289742	Tear Film Evaluation of Dailies® AquaComfort Plus® Multifocal and Toric	https://ClinicalTrials.gov/show/NCT02289742	Completed	Alcon Research	2015-03-31
NCT02255474	Bifocal Lenses In Nearsighted Kids	https://ClinicalTrials.gov/show/NCT02255474	Completed	Ohio State University	2019-06-24
NCT02252133	DAILIES TOTAL1® Lens Centration in a Japanese Population	https://ClinicalTrials.gov/show/NCT02252133	Completed	Alcon Research	2014-11-30
NCT02249689	Three-month Clinical Evaluation of Silicone Hydrogel Definitive 65 Contact Lenses	https://ClinicalTrials.gov/show/NCT02249689	Completed	Contamac Ltd	2014-01-31
NCT02235831	DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance	https://ClinicalTrials.gov/show/NCT02235831	Completed	Alcon Research	2014-10-31
NCT02214797	Dispensing Study to Assess Visual Performance of Prototype Contact Lenses	https://ClinicalTrials.gov/show/NCT02214797	Completed	Brien Holden Vision	2015-06-30
NCT02193555	Visual Performance of Prototype Contact Lens Designs	https://ClinicalTrials.gov/show/NCT02193555	Completed	Brien Holden Vision	2014-09-30
NCT02103309	Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan	https://ClinicalTrials.gov/show/NCT02103309	Completed	Alcon Research	2013-11-30
NCT02100410	On-Eye Evaluation of Contact Lens Axis Location	https://ClinicalTrials.gov/show/NCT02100410	Completed	Alcon Research	2013-04-30
NCT02089191	Tear Film Stability of DAILIES® AquaComfort Plus® Contact Lenses vs. MyDay® Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT02089191	Completed	Alcon Research	2014-04-30
NCT02072980	DAILIES TOTAL1® Lubricity Post Wear	https://ClinicalTrials.gov/show/NCT02072980	Completed	Alcon Research	2014-04-30
NCT02066922	A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects	https://ClinicalTrials.gov/show/NCT02066922	Completed	Alcon Research	2014-05-31
NCT02055404	On-Eye Evaluation of Contact Lens Rotation Marks	https://ClinicalTrials.gov/show/NCT02055404	Completed	Alcon Research	2013-02-28
NCT01997216	Multifocal Lens Design Evaluation	https://ClinicalTrials.gov/show/NCT01997216	Completed	Alcon Research	2012-11-30
NCT01996709	Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01996709	Completed	Alcon Research	2014-05-31
NCT01951573	Evaluation of a New Daily Disposable Multifocal Contact Lens Design	https://ClinicalTrials.gov/show/NCT01951573	Completed	Alcon Research	2013-11-30
NCT01941498	WaveLight® Refractive Myopic Study	https://ClinicalTrials.gov/show/NCT01941498	Completed	Alcon Research	2014-01-31
NCT01941485	WaveLight® Refractive Flap Accuracy Study	https://ClinicalTrials.gov/show/NCT01941485	Completed	Alcon Research	2014-01-31
NCT01917162	Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses (Study 2)	https://ClinicalTrials.gov/show/NCT01917162	Completed	Alcon Research	2013-11-30
NCT01912781	Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01912781	Completed	Alcon Research	2014-05-31
NCT01912768	Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01912768	Completed	Alcon Research	2014-05-31
NCT01875471	Clinical Evaluation of Two Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT01875471	Completed	Johnson & Johnson Vision Care, Inc.	2013-08-31
NCT01858701	Visual Performance Investigation of Two Toric Soft Contact Lenses	https://ClinicalTrials.gov/show/NCT01858701	Completed	Alcon Research	2013-10-31
NCT01839318	Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT01839318	Completed	Alcon Research	2013-06-30
NCT01809197	Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution	https://ClinicalTrials.gov/show/NCT01809197	Completed	Alcon Research	2013-07-31
NCT01782482	A Comparison of Two Color Contact Lenses in Habitual Clear Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01782482	Completed	Alcon Research	2013-04-30
NCT01706770	Evaluation of CooperVision Avaira Toric (Enfilcon A) Soft Contact Lens When Compared to Acuvue Advance Toric Soft Contact Lens	https://ClinicalTrials.gov/show/NCT01706770	Completed	Coopervision, Inc.	2012-07-31
NCT01699750	Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems	https://ClinicalTrials.gov/show/NCT01699750	Completed	Alcon Research	2013-11-30
NCT01675479	Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors	https://ClinicalTrials.gov/show/NCT01675479	Completed	Abbott Medical Optics	2016-10-31
NCT01663363	Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors	https://ClinicalTrials.gov/show/NCT01663363	Completed	Abbott Medical Optics	2014-03-31
NCT03349632	Clinical Comparison of 4 Daily Disposable Soft Contact Lenses	https://ClinicalTrials.gov/show/NCT03349632	Completed	Alcon Research	2018-02-16
NCT01629706	Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers	https://ClinicalTrials.gov/show/NCT01629706	Completed	Alcon Research	2014-01-31
NCT01582789	Comparative Study of Two Marketed Spherical Soft Contact Lenses	https://ClinicalTrials.gov/show/NCT01582789	Completed	Coopervision, Inc.	2012-05-31
NCT01484938	Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01484938	Completed	Alcon Research	2011-05-31
NCT01484054	Dispensing Evaluation of Subjective Comfort, Vision, and Handling of a New Lens Compared to a Marketed Lens	https://ClinicalTrials.gov/show/NCT01484054	Completed	Johnson & Johnson Vision Care, Inc.	2012-02-29
NCT01484028	Evaluation of the Performance of Two Contact Lenses Compared to a Marketed Lens	https://ClinicalTrials.gov/show/NCT01484028	Completed	Johnson & Johnson Vision Care, Inc.	2012-02-29
NCT01461811	Prospective Study of an Investigational Toric Soft Contact Lens	https://ClinicalTrials.gov/show/NCT01461811	Completed	Alcon Research	2012-04-30
NCT01440322	AIR OPTIX® COLORS Registration Trial	https://ClinicalTrials.gov/show/NCT01440322	Completed	Alcon Research	2012-01-31
NCT01430247	Vision Screening for the Detection of Amblyopia	https://ClinicalTrials.gov/show/NCT01430247	Completed	General Hospital Sveti Duh	2014-09-12
NCT01322919	Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure	https://ClinicalTrials.gov/show/NCT01322919	Completed	Technolas Perfect Vision GmbH	2012-02-29
NCT04437732	Apioc Presbyopic Contact Lens	https://ClinicalTrials.gov/show/NCT04437732	Recruiting	Lentechs, LLC	2020-10-31
NCT04254003	Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses	https://ClinicalTrials.gov/show/NCT04254003	Completed	Alcon Research	2020-03-02
NCT04156737	A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL	https://ClinicalTrials.gov/show/NCT04156737	Recruiting	Johnson & Johnson Surgical Vision, Inc.	2021-01-31
NCT04077086	Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities	https://ClinicalTrials.gov/show/NCT04077086	Recruiting	Queen’s University, Belfast	2022-07-01
NCT04075591	Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia	https://ClinicalTrials.gov/show/NCT04075591	Recruiting	Johnson & Johnson Surgical Vision, Inc.	2022-05-31
NCT04073238	Efficacy of Repeated Low-Level Red-Light Therapy in Myopia Control	https://ClinicalTrials.gov/show/NCT04073238	Recruiting	Zhongshan Ophthalmic Center, Sun Yat-sen University	2020-12-31
NCT04067141	The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT04067141	Completed	Coopervision, Inc.	2019-11-05
NCT04067050	A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices	https://ClinicalTrials.gov/show/NCT04067050	Completed	Coopervision, Inc.	2020-02-28
NCT04044755	Investigating the Effect of Using Myopia Prediction Algorithm on Myopia Children	https://ClinicalTrials.gov/show/NCT04044755	Recruiting	Sun Yat-sen University	2020-11-30
NCT04032457	PAVES Benchmarking Pilot Study of Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT04032457	Recruiting	Vision Service Plan	2019-10-31
NCT04013789	Comparison of Two Daily Disposable Lenses	https://ClinicalTrials.gov/show/NCT04013789	Completed	Alcon Research	2019-11-22
NCT03987880	Photorefractive Intrastromal Corneal Crosslinking as a Treatment for Low Grade Myopia	https://ClinicalTrials.gov/show/NCT03987880	Active, not recruiting	Umeå University	2020-03-22
NCT03983278	Perfecting Refraction in India With Superior Service Models	https://ClinicalTrials.gov/show/NCT03983278	Recruiting	Sun Yat-sen University	2020-03-21
NCT03971227	Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens	https://ClinicalTrials.gov/show/NCT03971227	Completed	Acuity Polymers, Inc.	2020-03-19
NCT03970512	Apioc Toric/Spherical Single Vision Contact Lens	https://ClinicalTrials.gov/show/NCT03970512	Recruiting	Lentechs, LLC	2020-10-31
NCT03969290	Clinical Performance of Two Daily Disposable Contact Lenses - Study 1	https://ClinicalTrials.gov/show/NCT03969290	Completed	Alcon Research	2019-08-05
NCT03888482	Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2	https://ClinicalTrials.gov/show/NCT03888482	Completed	Alcon Research	2019-06-28
NCT03888469	Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1	https://ClinicalTrials.gov/show/NCT03888469	Completed	Alcon Research	2019-06-24
NCT03835221	Performance of Toric Hydrogel Lenses Following A Refit With Toric Silicone Hydrogel Lenses for 1 Month	https://ClinicalTrials.gov/show/NCT03835221	Completed	Coopervision, Inc.	2019-03-27
NCT03835078	Performance of Aspheric Hydrogel Lenses After a Refit With Sphere Silicone Hydrogel Lenses for 4 Weeks	https://ClinicalTrials.gov/show/NCT03835078	Completed	Coopervision, Inc.	2019-03-27
NCT03762668	Performance Assessment of a Modified Daily Disposable Contact Lens	https://ClinicalTrials.gov/show/NCT03762668	Completed	Alcon Research	2019-01-07
NCT03688672	Apioc Contact Lens Feasibility	https://ClinicalTrials.gov/show/NCT03688672	Recruiting	Lentechs, LLC	2019-06-30
NCT03615612	Investigation of the Accuracy of a Low-cost, Portable, Autorefractor to Provide Well-tolerated Eyeglass Prescriptions	https://ClinicalTrials.gov/show/NCT03615612	Recruiting	Johns Hopkins University	2020-07-31
NCT03592615	Binocular Vision Anomalies After Cataract and Refractive Surgery	https://ClinicalTrials.gov/show/NCT03592615	Completed	Salus University	2019-11-26
NCT03567005	Clinical Validation of DACP Digital Design	https://ClinicalTrials.gov/show/NCT03567005	Completed	Alcon Research	2018-08-26
NCT03556579	The Effects of Contact Lenses With Experimental Dye on Visual Function	https://ClinicalTrials.gov/show/NCT03556579	Completed	Johnson & Johnson Vision Care, Inc.	2018-09-20
NCT03552016	Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure	https://ClinicalTrials.gov/show/NCT03552016	Recruiting	University of Missouri-Columbia	2021-10-10
NCT03518008	Clinical Comparison of Two Daily Disposable Soft Contact Lenses	https://ClinicalTrials.gov/show/NCT03518008	Completed	Alcon Research	2018-06-11
NCT03475875	Contact Lenses With New UV-blocker Manufactured With Different Techniques	https://ClinicalTrials.gov/show/NCT03475875	Completed	Johnson & Johnson Vision Care, Inc.	2018-04-18
NCT03459131	Clinical Evaluation of Two Monthly Contact Lenses	https://ClinicalTrials.gov/show/NCT03459131	Completed	Alcon Research	2018-03-26
NCT03455478	Shanghai Eye Study for Older People	https://ClinicalTrials.gov/show/NCT03455478	Recruiting	Shanghai Eye Disease Prevention and Treatment Center	2018-11-30
NCT01250925	Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface	https://ClinicalTrials.gov/show/NCT01250925	Completed	Massachusetts Eye and Ear Infirmary	2012-02-29
NCT01233089	Fitting Children With Contact Lenses	https://ClinicalTrials.gov/show/NCT01233089	Completed	Alcon Research	2011-08-31
NCT01220466	Performance and Acceptability of iDesign	https://ClinicalTrials.gov/show/NCT01220466	Completed	Abbott Medical Optics	2011-06-30
NCT01211535	Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers	https://ClinicalTrials.gov/show/NCT01211535	Completed	Alcon Research	2010-11-30
NCT01198600	Ocular Comfort and the “Aging” Lens (ERBIUM)	https://ClinicalTrials.gov/show/NCT01198600	Completed	Alcon Research	2011-07-31
NCT01163760	Clinical Evaluation of Two Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT01163760	Completed	Johnson & Johnson Vision Care, Inc.	2007-09-30
NCT01067716	Performance and Acceptability of VSS-R	https://ClinicalTrials.gov/show/NCT01067716	Completed	Abbott Medical Optics	2012-03-31
NCT01059019	Epithelial Healing and Visual Outcomes Using Omega-3 Therapy Before and After Photorefractive Keratectomy (PRK) Surgery	https://ClinicalTrials.gov/show/NCT01059019	Completed	University of California, San Diego	2011-05-31
NCT00950924	Optical Defocus to Stimulate Eye Elongation in Hyperopia	https://ClinicalTrials.gov/show/NCT00950924	Active, not recruiting	Aller, Thomas A., OD	2019-10-31
NCT00918697	Mechanical Versus Alcohol Epithelial Debridement During Hotorefractive Keratectomy (PRK)	https://ClinicalTrials.gov/show/NCT00918697	Completed	Shahid Beheshti University of Medical Sciences	NA
NCT03929588	Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye	https://ClinicalTrials.gov/show/NCT03929588	Recruiting	EyeQue Corp.	2020-01-31
NCT01741987	Osmoprotective Containing Lubricants in Dysfunctional Tear Syndrome and Post Refractive Surgery Patients	https://ClinicalTrials.gov/show/NCT01741987	Completed	Federal University of São Paulo	2012-10-31
NCT01827748	Evaluation of a Surgical Microscope Mounted Autorefractor When Used on Patients Lying in a Supine Position	https://ClinicalTrials.gov/show/NCT01827748	Completed	Adventus Technology	2013-03-31
NCT01797783	Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens	https://ClinicalTrials.gov/show/NCT01797783	Completed	Alcon Research	2013-04-30
NCT01444313	Prospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses	https://ClinicalTrials.gov/show/NCT01444313	Completed	Johnson & Johnson Vision Care, Inc.	2013-03-31
NCT02413333	Clear Care® Plus vs. PeroxiClearâ„¢	https://ClinicalTrials.gov/show/NCT02413333	Completed	Alcon Research	2015-08-31
NCT01898260	Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses	https://ClinicalTrials.gov/show/NCT01898260	Completed	Alcon Research	2013-10-31
NCT00762385	Clinical Comparison of Two Silicone-Hydrogel Contact Lenses	https://ClinicalTrials.gov/show/NCT00762385	Completed	Johnson & Johnson Vision Care, Inc.	2007-10-31
NCT00754338	Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens	https://ClinicalTrials.gov/show/NCT00754338	Completed	University of Waterloo	2008-07-31
NCT00725153	Evaluation of Deposits on Contact Lenses Worn Daily Wear	https://ClinicalTrials.gov/show/NCT00725153	Completed	Alcon Research	2008-09-30
NCT00722891	Ocular Responses to Short and Long-term Lens Wear	https://ClinicalTrials.gov/show/NCT00722891	Completed	Bausch & Lomb Incorporated	2009-06-30
NCT00721500	A Comparison of Two Daily Disposable Contact Lenses.	https://ClinicalTrials.gov/show/NCT00721500	Completed	Johnson & Johnson Vision Care, Inc.	2008-07-31
NCT00708643	Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population	https://ClinicalTrials.gov/show/NCT00708643	Completed	Johnson & Johnson Vision Care, Inc.	2008-09-30
NCT00708032	Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.	https://ClinicalTrials.gov/show/NCT00708032	Completed	Johnson & Johnson Vision Care, Inc.	2009-12-01
NCT00700752	A Comparison of Two Contact Lenses	https://ClinicalTrials.gov/show/NCT00700752	Completed	Johnson & Johnson Vision Care, Inc.	2008-07-31
NCT00691197	Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear	https://ClinicalTrials.gov/show/NCT00691197	Completed	Allergan	2008-10-31
NCT00657670	Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles	https://ClinicalTrials.gov/show/NCT00657670	Completed	Johns Hopkins University	2008-11-30
NCT00639379	Comparison of Two Toric Contact Lenses on Current Toric Wearers	https://ClinicalTrials.gov/show/NCT00639379	Completed	Johnson & Johnson Vision Care, Inc.	2008-06-30
NCT00630305	Endothelial Bleb Response With Toric Lenses	https://ClinicalTrials.gov/show/NCT00630305	Completed	Johnson & Johnson Vision Care, Inc.	2008-07-31
NCT00599950	Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C	https://ClinicalTrials.gov/show/NCT00599950	Completed	Asociación para Evitar la Ceguera en México	2007-01-31
NCT00597467	Study of Soft Contact Lens Use With 7 Day Extended Wear	https://ClinicalTrials.gov/show/NCT00597467	Completed	Coopervision, Inc.	2007-11-30
NCT00558324	Corneal Flap Thickness Planed vs Measured After LASIK by Using Tree Different Systems Cut	https://ClinicalTrials.gov/show/NCT00558324	Completed	Asociación para Evitar la Ceguera en México	NA
NCT00413881	A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures	https://ClinicalTrials.gov/show/NCT00413881	Completed	Walter Reed Army Medical Center	NA
NCT00371787	Evaluation of the Performance of Non-molded Soft Contact Lenses	https://ClinicalTrials.gov/show/NCT00371787	Completed	University of Waterloo	2007-12-31
NCT00365040	Customized PRK With Mitomycin Versus Customized Lasik for Myopic Astigmatism	https://ClinicalTrials.gov/show/NCT00365040	Completed	Federal University of São Paulo	NA
NCT00349063	Contact Lens Wettability	https://ClinicalTrials.gov/show/NCT00349063	Completed	University of Waterloo	NA
NCT00348621	A Study of Interventions to Reduce Disability From Visual Loss in Nursing Home Residents	https://ClinicalTrials.gov/show/NCT00348621	Completed	Johns Hopkins University	2001-12-31
NCT00347620	Improving Vision and Quality of Life in the Nursing Home	https://ClinicalTrials.gov/show/NCT00347620	Completed	University of Alabama at Birmingham	NA
NCT00317525	Effects of Different Add Powers on the Comfort and Productivity of Computer Users With Fixed or Free Head Movement	https://ClinicalTrials.gov/show/NCT00317525	Completed	American Optometric Association	NA
NCT00249275	Effectiveness of Alternative Approaches to Providing Spectacles in Tanzanian Secondary School Students	https://ClinicalTrials.gov/show/NCT00249275	Completed	London School of Hygiene and Tropical Medicine	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03334513	Refractive Error and Biometry in Retinopathy of Prematurity	https://ClinicalTrials.gov/show/NCT03334513	Completed	Changhua Christian Hospital	2014-04-01
NCT03292614	Measurement of Refractive SE Following Implantation of LS313 MF30 IOL	https://ClinicalTrials.gov/show/NCT03292614	Completed	Dietrich-Bonhoeffer-Klinikum	2019-01-31
NCT03030755	Corneal Elastography and Patient Specific Modeling	https://ClinicalTrials.gov/show/NCT03030755	Recruiting	The Cleveland Clinic	2020-05-31
NCT02889588	Visual and Optics Impact of Refractive Surgery	https://ClinicalTrials.gov/show/NCT02889588	Completed	Fondation Ophtalmologique Adolphe de Rothschild	2017-08-31
NCT02667509	The Evolutionary Model of Mild-to-moderate Myopia in China	https://ClinicalTrials.gov/show/NCT02667509	Completed	Sun Yat-sen University	2015-10-31
NCT02522416	A Comparison of Two Devices for Measuring the Central Thickness of the Cornea Before and After Surgery (CECOT)	https://ClinicalTrials.gov/show/NCT02522416	Completed	Fondation Ophtalmologique Adolphe de Rothschild	2017-01-30
NCT02519673	Comparison of Corneal Stromal Tissue Consumption (LATAC)	https://ClinicalTrials.gov/show/NCT02519673	Completed	Fondation Ophtalmologique Adolphe de Rothschild	2017-01-18
NCT02028351	Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions	https://ClinicalTrials.gov/show/NCT02028351	Completed	Sinclair Technologies, LLC	2009-03-31
NCT01663597	Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes	https://ClinicalTrials.gov/show/NCT01663597	Completed	Medical University of Vienna	2013-05-31
NCT01598818	First-Sight Refractive Error Correction in the Developing World	https://ClinicalTrials.gov/show/NCT01598818	Completed	University of Nebraska	2012-05-31
NCT01444053	Retrospective Study of the Health Benefits of Ultra-Violet Filtering Contact Lenses	https://ClinicalTrials.gov/show/NCT01444053	Completed	Johnson & Johnson Vision Care, Inc.	2011-12-01
NCT01342393	Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results	https://ClinicalTrials.gov/show/NCT01342393	Completed	University of Nebraska	2011-08-31
NCT04441268	Longitudinal Changes in Refractive Error After Primary IOL Implantation Among Children With Congenital Cataract	https://ClinicalTrials.gov/show/NCT04441268	Completed	Sun Yat-sen University	2019-12-30
NCT04429659	Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and Amblyopia	https://ClinicalTrials.gov/show/NCT04429659	Completed	Sakarya University	2019-04-01
NCT04346251	Correlation Between Refraction and Biometric Parameters	https://ClinicalTrials.gov/show/NCT04346251	Recruiting	Sun Yat-sen University	2019-11-30
NCT04338880	Academic Performance and Refractive Error	https://ClinicalTrials.gov/show/NCT04338880	Recruiting	Sun Yat-sen University	2019-06-30
NCT04249505	Refractive Accuracy of “2WIN” and Portable Autorefractors	https://ClinicalTrials.gov/show/NCT04249505	Recruiting	Alaska Blind Child Discovery	2020-03-31
NCT04161326	Environmental Health and Myopia Prevention and Control	https://ClinicalTrials.gov/show/NCT04161326	Recruiting	Sun Yat-sen University	2019-12-30
NCT04143334	Prevalence of Blindness, Visual Impairment in Chao Nan Area, China	https://ClinicalTrials.gov/show/NCT04143334	Completed	Chinese University of Hong Kong	2015-12-01
NCT03589937	Ocular Development and Refractive Error Changes Among Children and Adolescent - A Longitudinal Study	https://ClinicalTrials.gov/show/NCT03589937	Recruiting	Zhongshan Ophthalmic Center, Sun Yat-sen University	2021-07-20
NCT01173614	Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes	https://ClinicalTrials.gov/show/NCT01173614	Completed	European Vision Institute Clinical Research Network	2015-06-30
NCT00347347	Comparative Study of Cycloplegic Refraction and Subjective Refraction With Fogging in School Age Children	https://ClinicalTrials.gov/show/NCT00347347	Completed	Singapore National Eye Centre	2008-12-31
NCT00345085	Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses	https://ClinicalTrials.gov/show/NCT00345085	Completed	University of Texas Southwestern Medical Center	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03906279	Choroidal Thickness Change in Response to Physiological and Refractive Changes	https://ClinicalTrials.gov/show/NCT03906279	Recruiting	Wrocław University of Science and Technology	2024-02-29
NCT03893838	Chromatic and Monochromatic Optical Aberrations After Corneal Refractive Surgery	https://ClinicalTrials.gov/show/NCT03893838	Active, not recruiting	Wrocław University of Science and Technology	2022-02-01
NCT03668067	Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines	https://ClinicalTrials.gov/show/NCT03668067	Completed	Alaska Blind Child Discovery	2018-10-31